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For each interface, the source/destination check has to be disabled. Unless this is configured correctly, traffic from and to and an AWS instance will only be allowed if either source or destination address belongs to the instance. Transit traffic destined to be forwarded by the router, would be discarded.

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1. Create a configuration file (/etc/sysconfig/network-scripts/ifcfg-<interface-name>) for the second interface (if there is no configuration file for the primary interface, create it as well).
2. Set the correct interface for default route in /etc/sysconfig/network (example: GATEWAYDEV=eth0).
3. To prevent the cloud-init from resetting your custom network configurations, add the following lines to the /etc/cloud/cloud.cfg file:
   network:
  ; config: disabled
4. Restart the network.
5. Create an additional routing table (use the command: ip route add <path> dev <interface-name> table <table-id>). There must be an entry for every IP address assigned to the second interface and any other route to be used.
6. Set rules in the Routing Policy Database (use the command: ip rule add from <ip-address-of-second-interface> lookup <table-id>)
7. Create a static route file (/etc/sysconfig/network-scripts/route-<interface-name>)
8. Create a static rule file (/etc/sysconfig/network-scripts/rule-<interface-name>)

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